Articles  |   April 2018
SEE Question
Article Information
Cardiovascular Anesthesia / Central and Peripheral Nervous Systems / Education / CPD / Geriatric Anesthesia / Articles
Articles   |   April 2018
SEE Question
ASA Monitor 4 2018, Vol.82, 48.
ASA Monitor 4 2018, Vol.82, 48.
The authors of a recently published study investigated changes in cognitive function following transcatheter aortic valve replacement (TAVR). According to this study, which of the following statements is most likely true?
□ (A) In the majority of patients, there was global improvement in cognitive function regardless of pre-TAVR cognitive status.
□ (B) Patients with cognitive impairment pre-TAVR had the most profound cognitive decline.
□ (C) In the majority of patients, cognitive function declined over the first 30 days.
□ (D) In the majority of patients, cognitive function was found to be reduced only at one year.
The cognitive impact of TAVR was assessed in a recent study of 51 TAVR patients (median age 80 years). Prospective assessment of cognitive function was conducted using the Montréal Cognitive Assessment (MoCA) preoperatively and at 30 days and one year postoperatively. Processing speed and executive cognitive functions were also assessed using a digit-symbol substitution test, trail-making test, verbal fluency test and animal-naming test at the same time points. Cognitive decline was determined by changes in mean scores of each of these tests and the practice-adjusted reliable change index. The latter accounts for measurement errors and practice effects.
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