Articles  |   May 2016
ACE Question
Article Information
Education / CPD / Articles
Articles   |   May 2016
ACE Question
ASA Monitor 05 2016, Vol.80, 57.
ASA Monitor 05 2016, Vol.80, 57.
Leukocyte reduction of packed red blood cells (PRBCs) is most likely to result in a decreased risk of which of the following complications of transfusion?
Several European countries, including the United Kingdom and France, have adopted universal leukocyte reduction for all blood components. The American Red Cross advocated this practice in the United States officially in 2002. Since 1997, a majority of the packed red blood cells (PRBCs) transfused in the U.S. have undergone leukocyte reduction prior to storage. There are several well-described benefits of leukocyte reduction and many more hypothetical advantages that have yet to receive clinical validation. Leukocyte reduction of other blood product components (e.g., platelets or plasma) is considered to have potential benefits as well. In 2012, the U.S. Food and Drug Administration issued its final guidance for leukocyte reduction of PRBCs as a recommendation and not a requirement.
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