Articles  |   January 2018
ACE Question
Article Information
Education / CPD / Articles
Articles   |   January 2018
ACE Question
ASA Monitor 01 2018, Vol.82, 34.
ASA Monitor 01 2018, Vol.82, 34.
A patient with a history of anaphylaxis to penicillin is most likely to have an increased risk for cross-reactivity to which of the following generations of cephalosporin antibiotics?
Patient self-reporting of drug allergies is often an unreliable predictor of risk for anaphylaxis. Many patients report adverse experiences caused by predictable side effects or idiosyncratic reactions as “allergies.” Any drug given during the perioperative period has the potential to precipitate an immune hyper-sensitivity response. Some medications are capable of inducing histamine release or complement activation in the absence of an antigen-specific antibody, creating the same clinical manifestations as anaphylaxis.
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