Articles  |   July 2014
John W. Severinghaus Lecture on Translational Science – ‘Basic Science to Clinical Practice: The Tale of Long-Acting Opioids’
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Pain Medicine / Pharmacology / Quality Improvement / Articles
Articles   |   July 2014
John W. Severinghaus Lecture on Translational Science – ‘Basic Science to Clinical Practice: The Tale of Long-Acting Opioids’
ASA Monitor 07 2014, Vol.78, 42.
ASA Monitor 07 2014, Vol.78, 42.
This year’s John W. Severinghaus Lecture on Translational Science will be delivered by Evan D. Kharasch, M.D., Ph.D. Dr. Kharasch is Vice Chancellor for Research, Russell D. and Mary B. Sheldon Professor of Anesthesiology, and Director, Division of Clinical and Translational Research, Department of Anesthesiology, and Professor of Biochemistry and Molecular Biophysics, Washington University in St. Louis, St. Louis, Missouri.
The lecture will focus on opioids such as methadone that provide long-lasting relief of acute, perioperative, chronic and cancer pain, and which are pivotal to anesthesia practice. With an increase in methadone use, however, there has been a terrifying increase in untoward events. Only recently has there been a better understanding of methadone pharmacology, including pharmacokinetics, pharmacodynamics and pharmacogenetics.
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